Importance of lesion length on new device angioplasty of native coronary arteries

Author(s):  
Jorge F. Saucedo ◽  
Elizabeth D. Kennard ◽  
Jeffrey J. Popma ◽  
David Talley ◽  
Alexandra Lansky ◽  
...  
1996 ◽  
Vol 27 (2) ◽  
pp. 167-168 ◽  
Author(s):  
Simon R. Redwood ◽  
Jeffrey J. Popma ◽  
Kenneth M. Kent ◽  
Augusto D. Pichard ◽  
Lowell F. Satler ◽  
...  

2017 ◽  
Vol 24 (01) ◽  
pp. 21-25
Author(s):  
Naeem Asghar ◽  
Liaqat Ali ◽  
Asadullah -

Background: Coronary artery lesion severity is physiological assessed byfractional myocardial flow reserve (FFR). Angiographic assessment of intermediate severitylesions is problematic as inter-observer variability is significant. Hence one is not sure aboutthe hemodynamic or functional significance of these lesions. FFR is helpful in this situationby assessing functional or hemodynamic significance of these intermediate coronary lesions.An FFR value <0.80 identifies ischemia-causing coronary stenosis with an accuracy of >90%suggesting that intermediate coronary lesion is in fact functionally important. Objective: Todetermine the correlation between mean lesion length of diffuse intermediate stenosis (40%-70% stenosis) of proximal and mid segment of major coronary arteries and mean fractional flowreserve (FFR). Study duration: From 1-07-2015 to 31-12-2015. Study design: Cross sectionalstudy. Methodology: After approval from hospital Ethical committee and Informed consent, 60patients with intermediate diffuse lesions on coronary angiography from Faisalabad Institute ofCardiology were enrolled. FFR assessment of diffuse intermediate lesion was done by author.FFR assessment was done using FFR wire during maximal blood flow (hyperemia) whichwas induced by injecting bolus dose of intracoronary adenosine. The cost of procedure wasmanaged by hospital. Results: In this study, 28.33% (n=17) were between 20-50 years of age,mean+SD was calculated as 55.17+8.04 years, 51.67% (n=31) were male and 48.33% (n=29)were females. Correlation between mean lesion length of diffuse intermediate stenosis (40%-70% stenosis) of proximal and mid segment of major coronary arteries and mean fractionalflow reserve (FFR) was recorded it shows that mean lesion length was 24.53+4.78 mm whileFFR was recorded as 0.72+0.12, the value of R is -0.1928, technically a negative correlation,the relationship between variables is only weak (the nearer the value is to zero, the weakerthe relationship). The value of R2, the coefficient of determination, is 0.0372. Conclusion: Thecorrelation between mean lesion length of diffuse intermediate stenosis (40%-70% stenosis) ofproximal and mid segment of major coronary arteries and mean fractional flow reserve (FFR)was weak and did not suggest any hemodynamic significance of diffuse intermediate coronaryartery lesions.


1995 ◽  
Vol 25 (2) ◽  
pp. 122A ◽  
Author(s):  
Mun K. Hong ◽  
Jeffrey J. Popma ◽  
S. Chiu Wong ◽  
Kenneth M. Kent ◽  
Augusto D. Pichard ◽  
...  

2001 ◽  
Vol 28 (10) ◽  
pp. 943-949 ◽  
Author(s):  
Y. Amemori ◽  
S. Yamashita ◽  
M. Ai ◽  
H. Shinoda ◽  
M. Sato ◽  
...  

VASA ◽  
2004 ◽  
Vol 33 (4) ◽  
pp. 247-251 ◽  
Author(s):  
Zeller ◽  
Koch ◽  
Frank ◽  
Bürgelin ◽  
Schwarzwälder ◽  
...  

Diagnosis of non-specific aorto-arteritis (NSAA, Takaysu's arteritis) is typically based on clinical and investigational parameters. We report here about two patients with clinically suspected diagnosis of a Takayasu's arteritis already under anti-inflammatory therapy in whom percutaneous transluminal atherectomy of subclavian and axillary artery stenoses was performed to relief the patients from symptoms – intermittent dyspraxia of the arms – and to verify the clinical diagnosis by histology. In the first case aorto-arteritis could be histologically confirmed through the analysis of plaque material including media structures excised from the subclavian and axillary arteries using a new device for atherectomy. The biopsy showed diffuse inflammation and granulomatous lesions with giant cells typically for Takayasu's disease. In the second patient, biopsy showed no acute or chronic inflammatory signs but only atherosclerotic lesions. Percutaneous transluminal atherectomy is therefore not only an interventional but also a diagnostic tool and should be used in every case of interventional therapy of suspected aorto-arteritis to make the clinical diagnosis and as a major consequence the initiation of an aggressive anti-inflammatory medical therapy more reliable.


VASA ◽  
2017 ◽  
Vol 46 (6) ◽  
pp. 452-461 ◽  
Author(s):  
Klaus Amendt ◽  
Ulrich Beschorner ◽  
Matthias Waliszewski ◽  
Martin Sigl ◽  
Ralf Langhoff ◽  
...  

Abstract. Background: The purpose of this observational study is to report the six-month clinical outcomes with a new multiple stent delivery system in patients with femoro-popliteal lesions. Patients and methods: The LOCOMOTIVE study is an observational multicentre study with a primary endpoint target lesion revascularization (TLR) rate at six months. Femoro-popliteal lesions were prepared with uncoated and/or paclitaxel-coated peripheral balloon catheters. When flow limiting dissections, elastic recoil or recoil due to calcification required stenting, up to six short stents per delivery device, each 13 mm in length, were implanted. Sonographic follow-ups and clinical assessments were scheduled at six months. Results: For this first analysis, a total of 75 patients 72.9 ± 9.2 years of age were enrolled. The majority of the 176 individually treated lesions were in the superficial femoral artery (76.2 %, 134/176) whereas the rate of TASC C/D amounted to 51.1 % (90/176). The total lesion length was 14.5 ± 9.0 cm with reference vessel diameters of 5.6 ± 0.7 mm. Overall 47 ± 18 % of lesion lengths could be saved from stenting. At six months, the patency was 90.7 % (68/75) and all-cause TLR rates were 5.3 % (4/75) in the overall cohort. Conclusions: The first clinical experience at six months suggests that the MSDS strategy was safe and effective to treat femoro-popliteal lesions of considerable length (14.5 ± 9.0 cm). Almost half of the lesion length could be saved from stenting while patency was high and TLR rates were acceptably low.


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